Before DeSoto -- Hernando de Soto -- Santa Cruz de Sabacola -- Chislacasliche and Fort Apalachicola -- Ellicott's observatory -- Nicolls' outpost and the War of 1812 -- The "Negro fort" on the Apalachicola -- Scott's Massacre -- Andrew Jackson in Gadsden County -- First settlers and Neamathla's reserve -- The federal road -- King Cotton and Prince Tobacco -- Early scientists of Gadsden County -- The Comte de Castelnau -- The U.S. arsenal at Chattahoochee -- The Second Seminole War -- The McLane Massacre -- Seizure of the U.S. arsenal -- C.S.S. Chattahoochee -- Gadsden County and the Battle of Natural Bridge.